1. From The Zena and Michael A. Wiener Cardiovascular Institute (J.C.K., P.M., V.F.) and Marie-Josée and Henry R. Kravis Cardiovascular Health Center (V.F.), Mount Sinai School of Medicine, New York, NY; Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada (V.H.); Brigham and Women's Hospital, Boston, MA (E.G.N.); and Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (V.F.).