1. From the Center for Cardiovascular Disease Prevention (D.C., A.D.P., P.M.R.), the Donald W. Reynolds Center for Cardiovascular Research (D.C., A.D.P., P.M.R.), and the Division of Cardiovascular Medicine (M.A.C., P.M.R.) and Preventive Medicine (D.C., K.M.R., P.M.R., A.D.P.), Brigham and Women’s Hospital and Harvard Medical School, Boston, Mass; Department of Medicine (D.C.), University Hospital, Basel, Switzerland; and Division of Cardiology (A.D.P.), VA Boston Medical Center, Boston, Mass.