Glutaminolysis is Essential for Myofibroblast Persistence and In Vivo Targeting Reverses Fibrosis and Cardiac Dysfunction in Heart Failure-Reference-Cited by-同舟云学术

Glutaminolysis is Essential for Myofibroblast Persistence and In Vivo Targeting Reverses Fibrosis and Cardiac Dysfunction in Heart Failure

Published:2022-05-24 Issue:21 Volume:145 Page:1625-1628
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

Gibb Andrew A.¹^ORCID,Murray Emma K.¹^ORCID,Huynh Anh T.¹,Gaspar Ryan B.^ORCID,Ploesch Tori L.^ORCID,Bedi Ken²,Lombardi Alyssa A.¹,Lorkiewicz Pawel K.³^ORCID,Roy Rajika¹,Arany Zolt²^ORCID,Kelly Daniel P.²^ORCID,Margulies Kenneth B.²^ORCID,Hill Bradford G.⁴,Elrod John W.¹^ORCID

Affiliation:

1. Center for Translational Medicine, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA (A.A.G., E.K.M., A.T.H., R.B.G., T.L.P., A.A.L., R.R., J.W.E.).

2. Cardiovascular Institute and Cardiovascular Medicine Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (K.B., Z.A., D.P.K., K.B.M.).

3. Department of Chemistry (P.K.L.), University of Louisville, KY.

4. Division of Environmental Medicine (B.G.H.), University of Louisville, KY.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference5 articles.

1. Myofibroblasts and Fibrosis

2. Genetic lineage tracing defines myofibroblast origin and function in the injured heart

3. Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation

4. Genetic pharmacotherapy as an early CNS drug development strategy: testing glutaminase inhibition for schizophrenia treatment in adult mice.;Mingote S;Front Syst Neurosci,2015

5. The effect of metabolic acidosis on the synthesis and turnover of rat renal phosphate-dependent glutaminase

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