Recommendations for Statistical Reporting in Cardiovascular Medicine: A Special Report From the American Heart Association

Author:

Althouse Andrew D.1ORCID,Below Jennifer E.2ORCID,Claggett Brian L.3ORCID,Cox Nancy J.2,de Lemos James A.4ORCID,Deo Rahul C.3ORCID,Duval Sue5ORCID,Hachamovitch Rory6ORCID,Kaul Sanjay7ORCID,Keith Scott W.8ORCID,Secemsky Eric9ORCID,Teixeira-Pinto Armando10,Roger Veronique L.1112ORCID,

Affiliation:

1. Center for Research on Health Care Data Center, Division of General Internal Medicine, University of Pittsburgh, PA (A.D.A.).

2. Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN (J.E.B., N.J.C.).

3. Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (B.L.C., R.C.D.).

4. Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (J.A.d.L.).

5. Cardiovascular Division, University of Minnesota Medical School, Minneapolis (S.D.).

6. Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, OH (R.H.).

7. Department of Cardiology, Cedars-Sinai Medical Center, and the David Geffen School of Medicine, University of California, Los Angeles (S.K.).

8. Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA (S.W.K.).

9. Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA (E.S.).

10. School of Public Health, Faculty of Medicine and Health, University of Sydney, Australia (A.T.-P.).

11. Department of Cardiovascular Diseases Medicine, Mayo Clinic College of Medicine, Rochester, MN (V.L.R.)

12. now with Epidemiology and Community Health Branch National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD (V.L.R.).

Abstract

Statistical analyses are a crucial component of the biomedical research process and are necessary to draw inferences from biomedical research data. The application of sound statistical methodology is a prerequisite for publication in the American Heart Association (AHA) journal portfolio. The objective of this document is to summarize key aspects of statistical reporting that might be most relevant to the authors, reviewers, and readership of AHA journals. The AHA Scientific Publication Committee convened a task force to inventory existing statistical standards for publication in biomedical journals and to identify approaches suitable for the AHA journal portfolio. The experts on the task force were selected by the AHA Scientific Publication Committee, who identified 12 key topics that serve as the section headers for this document. For each topic, the members of the writing group identified relevant references and evaluated them as a resource to make the standards summarized herein. Each section was independently reviewed by an expert reviewer who was not part of the task force. Expert reviewers were also permitted to comment on other sections if they chose. Differences of opinion were adjudicated by consensus. The standards presented in this report are intended to serve as a guide for high-quality reporting of statistical analyses methods and results.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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