1. From the National University Heart Centre, Singapore, Singapore (M.Y.C.); Montreal Heart Institute, Montreal, Quebec, Canada (M.Y.C.); Duke Clinical Research Institute, Durham, NC (J.L.S., L.K.N., L.K.S., M.L., E.D.P., D.F.K., M.T.R.); and Duke Translational Medicine Institute, Durham, NC (R.M.C.).