1. From the Division of Cardiovascular Medicine and Department of Internal Medicine, Vanderbilt Heart and Vascular Institute, Nashville, TN (T.G.D.S.); Department of Medicine, Case Cardiovascular Research Institute, Case Western Reserve University School of Medicine, Cleveland, OH (S.M.H.); and Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH (S.M.H.).