1. From the Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (M.M.G., E.B.); Department of Medicine, Washington University, St. Louis, MO (D.L.M.); Department of Medicine, Duke University, Durham, NC (K.L.L., J.C.I., E.J.V., A.F.H.); and National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, Bethesda, MD (A.M.M.).