1. From the Department of Pediatrics (J.M., O.A.A., T.A., C.S.W., G.D.L.), Department of Pharmacology (J.M., O.A.A., T.A., C.S.W., G.D.L.), Mazankowski Alberta Heart Institute (J.M., V.B.P., O.A.A., R.B., T.A., J.D., C.S.W., Z.K., G.D.L., G.Y.O.), Department of Physiology (R.B., Z.K., G.Y.O.), and Division of Cardiology, Department of Medicine (V.B.P., J.D., G.Y.O.), University of Alberta, Edmonton, Canada.