1. From the Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy (S.B., M.G.F., E.R., S.M.); Gruppo Villa Maria Hospitals of Care and Research, ES Health Science Foundation, Cotignola, Italy (L.T.); Consorzio Mario Negri Sud, S Maria Imbaro, Chieti, Italy (R.M., G.T.); Department of Neurological and Behavioral Sciences, Section of Pharmacology “Giorgio Segre,” University of Siena, Siena, Italy (R.U.); ANMCO Research Centre, Florence, Italy (D.L., A.P.M.);...