1. From the Departments of Anatomy and Embryology (E.M.W., B.H., L.M.G., R.E.P., A.C.G.G.), Molecular Cell Biology (A.A.M.O., M.J.G.), and Cardiology (D.E.A.), Leiden University Medical Center, Leiden; and Department of Cardiology (P.D.), University Medical Center Utrecht, Utrecht, The Netherlands.