1. From the Department of Medicine (J.G.D.P., Y.M., M.A., H.J.R., F.B.), Division of Cardiology (J.G.D.P., Y.M., M.A., H.J.R., F.B.), Division of Cardiovascular Surgery, Department of Surgery (M.R., J.A., V.R.), Department of Medical Imaging, Peter Munk Cardiac Centre (B.J.W.), Ted Rogers Centre for Heart Research (M.R., H.J.R., F.B., V.R.), and Laboratory Medicine and Pathology (J.B.), Toronto General Hospital, University of Toronto, Canada.