1. From the Whitaker Cardiovascular Institute and Evans Department of Medicine, Boston University School of Medicine (G.R.U., G.N.W., J.E.F., A.J.F., A.P., A.M.S., C.S.A., J.F.K., J.L.), and Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School (G.R.U.), Boston, Mass.