The Influence of Experimentally Induced Atherosclerosis on the Sulfate Content of the Aortic Wall

Author:

FORMAN DONALD T.1,McCANN D. S.1,MOSHER R. E.1,BOYLE A. J.1

Affiliation:

1. Wayne State University, Department of Chemistry, Detroit 2, Mich

Abstract

By autoradiography it has been demonstrated that parenterally administered S 35 as sulfate is localized in the area of arterial plaque formation in rabbits with induced atherosclerosis. Dialysis of such tissue, after fat extraction to rid the tissue of inorganic sulfate, shows a much larger amount of sulfate remaining in the aortas of diseased animals as compared to controls suggesting that it is in combination with the mucopolysaccharides of the artery.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference4 articles.

1. Ca4B deposition during induced atherosclerosis;FORMAN D.;Indust. Mod.,1959

2. A study of arterial phosphorus in experimentally induced atherosclerosis;FORMAN D.;Indust. Mod.,1959

3. Utilization of S35-Labelled Sodium Sulphate in the Synthesis of Chondroitin Sulphuric Acid, Taurine, Methionine and Cystine.

4. Effects of hormones on the metabolism of acid mucopolysaccharides of connective tissue;DORFMAN A.;Recent Progress in Hormone Research,1958

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