1. From the Departments of Anesthesiology and Molecular Pharmacology and Experimental Therapeutics (M.A., D.E., D.W., Z.S.K.) and Division of Endocrinology and Metabolism (T.O’B.), Mayo Clinic and Foundation, Rochester, Minn; GenVec, Inc, Gaithersburg, Md (I.K.); and Department of Pharmacology and Molecular Cardiobiology Program, Yale University School of Medicine, New Haven, Conn (R.S.S., W.C.S.).