1. From the Institute for Biochemistry II, Goethe-University Frankfurt Medical School, Frankfurt/Main, Germany (I.K., M.M., A.E., T.H., M.H., S.O.); Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Giessen, Germany (B.K., R.T.S.); and Institute for Vascular Signalling, Goethe-University Frankfurt, Frankfurt/Main, Germany (V.R., K.K., I.F.).