Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone-Reference-Cited by-同舟云学术

Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone

Published:2018-02-16 Issue:4 Volume:122 Page:606-615
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circ Res

Author:

Good Miranda E.¹,Chiu Yu-Hsin¹,Poon Ivan K.H.¹,Medina Christopher B.¹,Butcher Joshua T.¹,Mendu Suresh K.¹,DeLalio Leon J.¹,Lohman Alexander W.¹,Leitinger Norbert¹,Barrett Eugene¹,Lorenz Ulrike M.¹,Desai Bimal N.¹,Jaffe Iris Z.¹,Bayliss Douglas A.¹,Isakson Brant E.¹,Ravichandran Kodi S.¹

Affiliation:

1. From the Department of Molecular Physiology and Biophysics, Robert M. Berne Cardiovascular Research Center (M.E.G., J.T.B., L.J.D., A.W.L., B.E.I.), Department of Pharmacology (Y.-H.C., S.K.M., N.L., B.N.D., D.A.B.), Department of Microbiology, Immunology and Cancer Biology, the Center for Cell Clearance, and the Beirne B. Carter Center for Immunology Research (C.B.M., U.M.L., K.S.R.), and Division of Endocrinology (E.B.), University of Virginia School of Medicine, Charlottesville; Department of...

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference43 articles.

1. Purinergic regulation of the immune system

2. Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

3. Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock

4. Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival

5. A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells

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