1. From the Cardiovascular Division, British Heart Foundation Centre, King’s College London, UK (E.K., A.M., B.W., X.W., X.H., M.M.W., C.M.S., A.M.S., Y.H., Q.X.); The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK (D.B., J.R.); and Chinese Academy of Sciences Key Laboratory of Computational Biology, Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Shanghai, China (Y.H., J.-D.J.H., H.Y.).