1. From the Division of Cardiovascular Medicine, the Department of Medicine, Brigham and Women's Hospital, and the Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA (J.M.); the Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX (R.A.D.); and the Huffington Center on Aging and the Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX (E.S.).