Short Communication: Flecainide Exerts an Antiarrhythmic Effect in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia by Increasing the Threshold for Triggered Activity-Reference-Cited by-同舟云学术

Short Communication: Flecainide Exerts an Antiarrhythmic Effect in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia by Increasing the Threshold for Triggered Activity

Published:2011-07-22 Issue:3 Volume:109 Page:291-295
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circ Res

Author:

Liu Nian¹,Denegri Marco¹,Ruan Yanfei¹,Avelino-Cruz José Everardo¹,Perissi Andrea¹,Negri Sara¹,Napolitano Carlo¹,Coetzee William A.¹,Boyden Penelope A.¹,Priori Silvia G.¹

Affiliation:

1. From the Cardiovascular Genetics Program (N.L., Y.R., C.N., S.G.P.), The Leon H. Charney Division of Cardiology, and the Departments of Pediatrics, Physiology and Neuroscience, and Pharmacology (W.A.C.), New York University School of Medicine, New York, NY; Molecular Cardiology (M.D., J.E.A.-C., C.N., S.G.P.) and Centro ricerche ambientali (A.P., S.N.), IRCCS Fondazione Salvatore Maugeri, Pavia, Italy; Department of Pharmacology (P.A.B.), Columbia College of Physicians and Surgeons, New York, NY;...

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference7 articles.

1. Catecholaminergic Polymorphic Ventricular Tachycardia

2. Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

3. Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass

4. Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia

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