Endothelial SIRT6 Is Vital to Prevent Hypertension and Associated Cardiorenal Injury Through Targeting Nkx3.2-GATA5 Signaling

Author:

Guo Jian1,Wang Ziying1,Wu Jichao1,Liu Min1,Li Mengmeng2,Sun Yu1,Huang Wei1,Li Yujia1,Zhang Yan1,Tang Wei3,Li Xiaoyan4,Zhang Chun5,Hong Fanzhen6,Li Ningjun7,Nie Jing8,Yi Fan1

Affiliation:

1. From the Key Laboratory of Infection and Immunity of Shandong Province, Department of Pharmacology (J.G., Z.W., J.W., M. Liu, W.H., Y.L., Y.Z., F.Y.), Shandong University, Jinan, China

2. School of Basic Medical Science, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital (M. Li), Shandong University, Jinan, China

3. Department of Pathogenic Biology, School of Basic Medical Science (W.T.), Shandong University, Jinan, China

4. Shandong Provincial Key Laboratory of Oral Biomedicine, Department of Endodontics, School of Stomatology (X.L.), Shandong University, Jinan, China

5. Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (C.Z.)

6. Department of Obstetrics and Gynecology, Second Hospital of Shandong University, Jinan, China (F.H.)

7. Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond (N.L.)

8. State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China (J.N.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

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