1. From the Wolfson Drug Discovery Unit, and the National Amyloidosis Centre, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London, United Kingdom (M.B.P., T.L., H.J.L., J.D.G., P.N.H.); Department of Clinical Biochemistry, Royal Free Hospital, London, United Kingdom (N.W.); and the National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, United Kingdom (S.P., Y.M.).