1. Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (P.Y., P.B.Y.). Now with State Key Laboratory of Medical Molecular Biology, Department of Physiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China (P.Y.). Now with Cardiovascular Research Center, Division of Cardiovascular Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA (P.B.Y.).