Discussion of Reports on Renoprival Hypertension

Abstract

It was pointed out that some of the confusion in this field resulted from failure to define the term "hypertension." A simple rise in blood pressure was not hypertensive disease and should not be referred to as "hypertension" according to Dr. Grollman. It was stated that all hypertension is renal in origin, but due to a defect in the function rather than in the circulation of the kidney (Dr. Grollman). In both renal and renoprival hypertension there is lack of the normal renal protective mechanism, i.e., the kidneys fail to excrete some pressor substance (Dr. Handler). This protective action of the kidneys may be metabolic rather than excretory, and both renal and renoprival hypertension may be due to the lack of renal catabolism of pressor materials which may be of extrarenal as well as of renal origin (Dr. Rodbard and others).