Frailty and Cardiovascular Health-Reference-Cited by-同舟云学术

Frailty and Cardiovascular Health

Published:2024-08-06 Issue:15 Volume:13 Page:
ISSN:2047-9980
Container-title:Journal of the American Heart Association
language:en
Short-container-title:JAHA

Author:

James Kirstyn¹^ORCID,Jamil Yasser²^ORCID,Kumar Manish³^ORCID,Kwak Min J.⁴^ORCID,Nanna Michael G.²^ORCID,Qazi Saadia⁵^ORCID,Troy Aaron L.⁶^ORCID,Butt Jawad H.⁷⁸⁹^ORCID,Damluji Abdulla A.¹⁰¹¹^ORCID,Forman Daniel E.¹²¹³^ORCID,Orkaby Ariela R.⁵¹⁴^ORCID

Affiliation:

1. Department of Geriatric Medicine Cork University Hospital Cork Ireland

2. Department of Internal Medicine Yale University School of Medicine New Haven CT USA

3. University of Connecticut Hartford CT USA

4. University of Texas Health Science Center at Houston TX USA

5. VA Boston Healthcare System Boston MA USA

6. Department of Medicine Beth Israel Deaconess Medical Center Boston MA USA

7. British Heart Foundation Cardiovascular Research Centre University of Glasgow UK

8. Department of Cardiology Rigshospitalet Copenhagen University Hospital Copenhagen Denmark

9. Department of Cardiology Zealand University Hospital Roskilde Denmark

10. Johns Hopkins University School of Medicine Baltimore MD USA

11. The Inova Center of Outcomes Research Inova Heart and Vascular Institute Baltimore MD USA

12. Department of Medicine (Geriatrics and Cardiology) University of Pittsburgh PA USA

13. Pittsburgh GRECC (Geriatrics Research, Education and Clinical Center) VA Pittsburgh Healthcare System Pittsburgh PA USA

14. Division of Aging, Brigham and Women’s Hospital Harvard Medical School Boston MA USA

Abstract

The incidence of frailty and cardiovascular disease (CVD) increases as the population ages. There is a bidirectional relationship between frailty and CVD, and both conditions share several risk factors and underlying biological mechanisms. Frailty has been established as an independent prognostic marker in patients with CVD. Moreover, its presence significantly influences both primary and secondary prevention strategies for adults with CVD while also posing a barrier to the inclusion of these patients in pivotal clinical trials and advanced cardiac interventions. This review discusses the current knowledge base on the relationship between frailty and CVD, how managing CVD risk factors can modify frailty, the influence of frailty on CVD management, and future directions for frailty detection and modification in patients with CVD.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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