Was COVID‐19 Associated With Worsening Inequities in Stroke Treatment and Outcomes?

Author:

Glance Laurent G.123ORCID,Benesch Curtis G.4,Joynt Maddox Karen E.56ORCID,Bender Matthew T.7,Shang Jingjing8,Stone Patricia W.8ORCID,Lustik Stewart J.1,Nadler Jacob W.1,Galton Christopher1ORCID,Dick Andrew W.3

Affiliation:

1. Department of Anesthesiology and Perioperative Medicine University of Rochester School of Medicine Rochester NY

2. Department of Public Health Sciences University of Rochester School of Medicine Rochester NY

3. RAND Health, RAND Boston MA

4. Department of Neurology University of Rochester School of Medicine Rochester NY

5. Department of Medicine Washington University in St. Louis St. Louis MO

6. Center for Health Economics and Policy at the Institute for Public Health Washington University in St. Louis St. Louis MO

7. Department of Neurosurgery University of Rochester School of Medicine Rochester NY

8. Columbia School of Nursing, Center for Health Policy New York NY

Abstract

Background COVID‐19 stressed hospitals and may have disproportionately affected the stroke outcomes and treatment of Black and Hispanic individuals. Methods and Results This retrospective study used 100% Medicare Provider Analysis and Review file data from between 2016 and 2020. We used interrupted time series analyses to examine whether the COVID‐19 pandemic exacerbated disparities in stroke outcomes and reperfusion therapy. Among 1 142 560 hospitalizations for acute ischemic strokes, 90 912 (8.0%) were Hispanic individuals; 162 752 (14.2%) were non‐Hispanic Black individuals; and 888 896 (77.8%) were non‐Hispanic White individuals. The adjusted odds of mortality increased by 51% (adjusted odds ratio [aOR], 1.51 [95% CI, 1.34–1.69]; P <0.001), whereas the rates of nonhome discharges decreased by 11% (aOR, 0.89 [95% CI, 0.82–0.96]; P =0.003) for patients hospitalized during weeks when the hospital's proportion of patients with COVID‐19 was >30%. The overall rates of motor deficits ( P =0.25) did not increase, and the rates of reperfusion therapy did not decrease as the weekly COVID‐19 burden increased. Black patients had lower 30‐day mortality (aOR, 0.70 [95% CI, 0.69–0.72]; P <0.001) but higher rates of motor deficits (aOR, 1.14 [95% CI, 1.12–1.16]; P <0.001) than White individuals. Hispanic patients had lower 30‐day mortality and similar rates of motor deficits compared with White individuals. There was no differential increase in adverse outcomes or reduction in reperfusion therapy among Black and Hispanic individuals compared with White individuals as the weekly COVID‐19 burden increased. Conclusions This national study of Medicare patients found no evidence that the hospital COVID‐19 burden exacerbated disparities in treatment and outcomes for Black and Hispanic individuals admitted with an acute ischemic stroke.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Reference43 articles.

1. Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

2. Stroke and African Americans . U.S. Department of Health and Human Services Office of Minority Health. 2022. Accessed April 13 2022. https://minorityhealth.hhs.gov/omh/browse.aspx?lvl=4&lvlid=28#:~:text=African%20Americans%20are%2050%20percent compared%20to%20non%2DHispanic%20whites.

3. Deaths: final data for 2018;Murphy SL;Natl Vital Stat Rep,2021

4. Racial disparities in severity of cerebrovascular events.

5. Racial Variation in Initial Stroke Severity

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