Composition and State of Protein in Heart Muscle of Normal Dogs and Dogs with Experimental Myocardial Failure

Author:

BENSON ELLIS S.1

Affiliation:

1. Departments of Medicine, Pathology and Surgery and the Hospital Laboratories, University of Minnesota Medical School Minneapolis, Minnesota and the Surgical Service, Ancker Hospital, St. Paul, Minnesota

Abstract

In comparing protein composition of cardiac muscle of normal dogs and dogs with experimental valvular lesions and chronic heart failure, it was found that the concentration of actomyosin was lower in the experimental than in normal dogs. Furthermore, cardiac actomyosin in the experimental animals showed decreased viscosity, decreased viscosity response to ATP, and sedimentation patterns that differed from the normal.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference10 articles.

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3. Histochemical changes associated with aging. I. Methods and calculations;LOWHY H.;J. Biol. Chem.,1942

4. Extraction and Quantitative Characteristics of Actomyosin in Canine Heart Muscle

5. A reference base and system for analysis of muscle constituents;LLLIENTHAL J. L.;J. Biol. Chem.,1950

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