The Therapeutic Range of Gitalin (Amorphous) Compared with Other Digitalis Preparations-Reference-Cited by-同舟云学术

The Therapeutic Range of Gitalin (Amorphous) Compared with Other Digitalis Preparations

Published:1952-02 Issue:2 Volume:5 Page:201-207
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

BATTERMAN ROBERT C.¹,DEGRAFF ARTHUR C.¹,ROSE O. ALAN¹

Affiliation:

1. From the Department of Therapeutics and the Cardiac Clinic, New York University-Bellevue Medical Center; the Adult Cardiac Clinic and Third (New York University) Medical Division, Bellevue Hospital; the Medical Service, Lenox Hill Hospital; and the Cardiac Section of the Medical Service, Bronx Veterans Hospital, New York, N. Y.

Abstract

The therapeutic ranges of amorphous gitalin, digitalis leaf, digitoxin and Digoxin were compared in terms of rapid and slow methods for initial digitalization and maintenance of the digitalized patient. Gitalin (amorphous) possesses a therapeutic range greater than any available digitalis preparation or glycoside. In a group of 18 ambulatory patients, gitalin (amorphous) was found to possess an average of 41 per cent increase in therapeutic range when compared with digitalis leaf. Advantages of the use of gitalin (amorphous) as compared with other digitalis preparations are discussed.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.5.2.201

Reference7 articles.

1. 1 BATTERMAN , R. C. , DEGRAFF , A. C. , GUTNER , L. B. , RosE, 0. A., AND LHOWE, J.: Studies with gitalin (amorphous) for the treatment of patient 3 with congestive heart failure. Am. Heart J. 42: 292, 151.

2. Clinical studies on digoxin, a purified digitalis glycoside

3. The combined use of ouabain and digitalis in the treatment of congestive heart failure

4. THE THERAPEUTIC EFFECTIVENESS AND POTENCY OF DIGILANID IN THE TREATMENT OF CONGESTIVE HEART FAILURE

5. Unpublished data.

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1. Pharmakodynamik von Gitoformat;Gitoformat — ein nicht-nierenpflichtiges Digitalisglykosid;1984

2. Different Toxic Effects of Ouabain and 16-Epi-Gitoxin on Purkinje Fibres and Ventricular Muscle Fibres;Pharmacology;1976

3. Diagnostic de l’intoxication digitalique et son traitement;Cardiology;1967

4. A Comparison of Digitalis Intoxication in Two Separate Periods;Annals of Internal Medicine;1965-05-01

5. Trial by digitalis;American Heart Journal;1964-04