Nitroprusside after open-heart surgery.

Author:

Benzing G,Helmsworth J A,Schrieber J T,Loggie J,Kaplan S

Abstract

The effects of intravenous infusion of sodium nitroprusside were studied in 11 children immediately after open-heart surgery for congenital heart disease. The patients were selected because, following bypass, their cardiac index was below 2,0 L/min/m2 and their systemic vascular resistance exceeded 30 units. In order to eliminate the effects of preload, mean left atrial pressure was maintained at a constant level by blood transfusion. During infusion of nitroprusside the mean decrease of mean arterial pressure was 18.6%, of systemic vascular resistance was 53.7%, and the increase in cardiac index was 76.9%. All children recovered.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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1. Experts’ recommendations for the management of cardiogenic shock in children;Annals of Intensive Care;2016-02-16

2. Postoperative Critical Care of the Adult Cardiac Surgical Patient. Part I;Critical Care Medicine;2015-07

3. Pharmacologic Treatment of Heart Disease;Pediatric Cardiology;2006

4. Pharmacology of Cardiovascular Drugs;Critical Heart Disease in Infants and Children;2006

5. CARDIOVASCULAR ASPECTS;Assisted Ventilation of the Neonate;2003

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