1. From the Department of Neurology (A.G.K.), University of Rochester Medical Center, Rochester, NY; Duke Clinical Research Institute (A.S.H., D.O.), Durham, NC; the Department of Clinical Neurosciences (E.E.S.), Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; and the Department of Neurology (L.H.S.), Massachusetts General Hospital, Harvard Medical School, Boston, MA.