1. From the Department of Cardiovascular Medicine, Heart and Vascular Institute, Case Western Reserve University, MetroHealth Campus, Cleveland, OH (G.A., P.C.); Department of Cardiovascular Medicine, Tufts School of Medicine, Boston, MA (E.P.); and Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, OH (R.D.G., E.M.T., S.R.K.).