Uncertainties and Controversies in the Management of Ischemic Stroke and Transient Ischemic Attack Patients With Patent Foramen Ovale-Reference-Cited by-同舟云学术

Uncertainties and Controversies in the Management of Ischemic Stroke and Transient Ischemic Attack Patients With Patent Foramen Ovale

Published:2021-12 Issue:12 Volume:52 Page:
ISSN:0039-2499
Container-title:Stroke
language:en
Short-container-title:Stroke

Author:

Kasner Scott E.¹^ORCID,Lattanzi Simona²^ORCID,Fonseca Ana Catarina³^ORCID,Elgendy Akram Y.⁴⁵

Affiliation:

1. Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (S.E.K.).

2. Department of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy (S.L.).

3. Department of Neurology, Centro Hospitalar Universitário Lisboa Norte, Faculdade de Medicina, Universidade de Lisboa, Portugal (A.C.F.).

4. Division of Cardiovascular Medicine, University of California San Francisco (A.Y.E.).

5. Division of Cardiovascular Medicine, Harrington Heart and Vascular Institute, Case Western Reserve University, Cleveland, OH (A.Y.E.).

Abstract

Abstract: Multiple randomized clinical trials have demonstrated the benefit of patent foramen ovale closure over medical therapy alone for patients who have had a stroke that has been attributed to the patent foramen ovale. Nevertheless, there are many areas of uncertainty and controversy related to patient selection, pathophysiology, diagnosis, and treatment. We summarize the available data on these challenging topics and attempt to provide some clarity and future directions for clinicians and investigators.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology

Link

https://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.121.034778

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