Priorities for Advancements in Neuroimaging in the Diagnostic Workup of Acute Stroke

Author:

Samaniego Edgar A.1ORCID,Boltze Johannes2ORCID,Lyden Patrick D.3ORCID,Hill Michael D.4ORCID,Campbell Bruce C.V.5ORCID,Silva Gisele Sampaio6ORCID,Sheth Kevin N.7,Fisher Marc8ORCID,Hillis Argye E.9ORCID,Nguyen Thanh N.10ORCID,Carone Davide11,Favilla Christopher G.12ORCID,Deljkich Emir13ORCID,Albers Gregory W.14ORCID,Heit Jeremy J.15ORCID,Lansberg Maarten G.14ORCID,Aksoy Didem,Broderick Joe,Castonguay Alicia C.,Ghosh Supurna,Grotta James C.,Harston George,Houser Gary R.,Kuchenbecker Kristopher,Latour Lawrence L.,Liebeskind David S.,Kylan Lynch John,Maier Carolina,Mistry Eva,Mocco J.,Nogueira Raul G.,Saver Jeffrey L.,van Vlimmeren Marijke,Wakhloo Ajay K.,Wechsler Lawrence

Affiliation:

1. Department of Neurology, Radiology and Neurosurgery, University of Iowa Carver College of Medicine (E.A.S.).

2. School of Life Sciences, University of Warwick, Coventry, United Kingdom (J.B.).

3. Zilkha Neurogenetic Institute of the Keck School of Medicine at USC, Los Angeles, CA (P.D.L.).

4. Department of Clinical Neuroscience and Hotchkiss Brain Institute, University of Calgary and Foothills Medical Centre, Canada (M.D.H.).

5. Department of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia (B.C.V.C.).

6. Department of Neurology and Neurosurgery, Federal University of São Paulo, Brazil (G.S.S.).

7. Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale School of Medicine, New Haven, CT (K.N.S.).

8. Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA (M.F.).

9. Department of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD (A.E.H.).

10. Department of Neurology, Boston Medical Center, MA (T.N.N.).

11. Oxford University Hospitals NHS Foundation Trust, United Kingdom (D.C.).

12. Department of Neurology, University of Pennsylvania Philadelphia (C.G.F.).

13. Imperative Care (E.D.).

14. Departments of Neurology (G.W.A., M.G.L.), Stanford University, CA.

15. Radiology and Neurosurgery (J.J.H.), Stanford University, CA.

Abstract

STAIR XII (12th Stroke Treatment Academy Industry Roundtable) included a workshop to discuss the priorities for advancements in neuroimaging in the diagnostic workup of acute ischemic stroke. The workshop brought together representatives from academia, industry, and government. The participants identified 10 critical areas of priority for the advancement of acute stroke imaging. These include enhancing imaging capabilities at primary and comprehensive stroke centers, refining the analysis and characterization of clots, establishing imaging criteria that can predict the response to reperfusion, optimizing the Thrombolysis in Cerebral Infarction scale, predicting first-pass reperfusion outcomes, improving imaging techniques post-reperfusion therapy, detecting early ischemia on noncontrast computed tomography, enhancing cone beam computed tomography, advancing mobile stroke units, and leveraging high-resolution vessel wall imaging to gain deeper insights into pathology. Imaging in acute ischemic stroke treatment has advanced significantly, but important challenges remain that need to be addressed. A combined effort from academic investigators, industry, and regulators is needed to improve imaging technologies and, ultimately, patient outcomes.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Neurology (clinical)

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