Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease-Reference-Cited by-同舟云学术

Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease

Published:2019-03 Issue:3 Volume:50 Page:738-744
ISSN:0039-2499
Container-title:Stroke
language:en
Short-container-title:Stroke

Author:

Shenkar Robert¹,Peiper Amy²,Pardo Heidy²,Moore Thomas¹,Lightle Rhonda¹,Girard Romuald¹,Hobson Nicholas¹,Polster Sean P.¹,Koskimäki Janne¹,Zhang Dongdong¹,Lyne Seán B.¹,Cao Ying¹,Chaudagar Kiranj¹,Saadat Laleh¹,Gallione Carol²,Pytel Peter³,Liao James K.⁴,Marchuk Douglas²,Awad Issam A.¹

Affiliation:

1. From the Section of Neurosurgery (R.S., T.M., R.L., R.G., N.H., S.P.P., J.K., D.Z., S.B.L., Y.C., K.C., L.S., I.A.A.), Biological Sciences Division, University of Chicago, IL

2. Molecular Genetics and Microbiology Department, Duke University Medical Center, Durham, NC (A.P., H.P., C.G., D.M.).

3. Department of Pathology (P.P.), Biological Sciences Division, University of Chicago, IL

4. Section of Cardiology (J.K.L.), Biological Sciences Division, University of Chicago, IL

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Neurology (clinical)

Reference44 articles.

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2. A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease

3. Strategy for Identifying Repurposed Drugs for the Treatment of Cerebral Cavernous Malformation

4. KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling.;DiStefano PV;J Biol Chem,2014

5. Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice

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