1. From the Departments of Pharmacology (R.A.P.S., F.M.F., D.D.H.) and Internal Medicine (Y.C., I.J.M., F.M.F., D.D.H.), University of Iowa, College of Medicine, Iowa City, IA; Medical School, Universidad de los Andes, Bogota, Colombia (R.A.P.S.); Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN (J.D.M.); and Institute for Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria (J.M.P.).