The Role of the Sympathetic Nervous System in Lipid Deposition. I. Increased Lipid Deposits in the Iris of the Sympathectomized Eye in Rabbits Fed an Atherogenic Diet-Reference-Cited by-同舟云学术

The Role of the Sympathetic Nervous System in Lipid Deposition. I. Increased Lipid Deposits in the Iris of the Sympathectomized Eye in Rabbits Fed an Atherogenic Diet

Published:1971-01 Issue:1 Volume:2 Page:23-34
ISSN:0039-2499
Container-title:Stroke
language:en
Short-container-title:Stroke

Author:

AUSTIN JAMES¹,ROBERTS WILLIAM¹,NEVILLE HANS¹,ARMSTRONG DONALD¹

Affiliation:

1. The Division of Neurology, University of Colorado Medical Center, Denver, Colorado, 80220

Abstract

Rabbits on a high-cholesterol diet deposit more lipid in the iris of the sympathectomized eye. Histologically, the lipid deposits are composed of sudanophilic staining droplets localized both in smooth muscle cell cytoplasm of the iris dilator muscle and in larger oval cells. Possible metabolic and vascular mechanisms are noted which may underlie these findings. Potential clinical implications of these findings are cited.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.STR.2.1.23

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1. Rapid development of atherosclerotic lesions in the rabbit carotid artery induced by perivascular manipulation;Atherosclerosis;1989-04

2. The sympathetic nervous system and atherosclerosis;Journal of Neurosurgery;1987-12

3. Trophic effect of the sympathetic nervous system on vascular smooth muscle;Annals of Biomedical Engineering;1983-11

4. Combined effect of cholesterol feeding and sympathectomy on the lipid content in rabbit aortas;Atherosclerosis;1980-12

5. Effect of long-term sympathectomy on the arterial wall in rabbits and rats;Experimental and Molecular Pathology;1978-06