Effect of nitroglycerin on cerebral circulation measured by transcranial Doppler and SPECT.

Author:

Dahl A1,Russell D1,Nyberg-Hansen R1,Rootwelt K1

Affiliation:

1. Department of Neurology, Rikshospitalet, National Hospital, University of Oslo, Norway.

Abstract

We used a combination of transcranial Doppler ultrasonography and single-photon emission computed tomography to noninvasively assess changes in the diameter of the middle cerebral artery induced by sublingual nitroglycerin in 10 healthy subjects. Nitroglycerin reduced mean blood flow velocities without concurrently changing regional cerebral blood flow in the perfusion territory of this vessel. Our results strongly suggest that nitroglycerin causes vasodilatation of the basal intracranial arteries.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology

Reference11 articles.

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4. Effects of Nitroglycerin on the Diameter of Intracranial and Extracranial Arteries in Monkeys

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