Postpartum Cerebral Angiopathy Possibly Due to Bromocriptine Therapy

Author:

Janssens E.1,Hommel M.1,Mounier-Vehier F.1,Leclerc X.1,du Masgenet B. Guerin1,Leys D.1

Affiliation:

1. From the Departments of Neurology (E.J., F.M.-V., D.L.) and Neuroradiology (X.L.), Lille University Hospital; the Department of Obstetrics, Wattrelos Hospital (B.G. du M.); and the Department of Neurology, Grenoble University Hospital (M.H.) (France).

Abstract

Background Eight cases of benign angiopathy of the postpartum period have been reported previously, none of which involved the administration of bromocriptine. Case Description We describe a case of benign cerebral angiopathy in a 20-year-old woman in the postpartum period occurring after bromocriptine therapy prescribed to suppress lactation. Conclusions Other adverse effects due to vasoconstriction have been reported during bromocriptine therapy, such as myocardial infarction and arterial hypertension. This case suggests that a similar mechanism may be possible in cerebral arteries, although the cause of vasoconstriction remains uncertain.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology

Reference10 articles.

1. Rascol A Guiraud B Manelfe C Clanet M. Accidents vasculaires cérébraux de la grossesse et du post-partum. In: 2th Conférence de la Salpétrière sur les Maladies Vasculaires Cérébrales 1979. Paris France: JB Baillière; 1980:84-127.

2. Postpartum Cerebral Angiopathy: Reversible Vasoconstriction Assessed by Transcranial Doppler Ultrasounds

3. Cerebrovascular Complications of the Use of the Crack Form of Alkaloidal Cocaine

4. Intracranial hemorrhage with amphetamine abuse

5. Reversible Cerebral Arteriopathy Associated with the Administration of Ergot Derivatives

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