Cerebral infarction immediately after ingestion of hydrogen peroxide solution.

Author:

Sherman S J1,Boyer L V1,Sibley W A1

Affiliation:

1. Department of Neurology, University of Arizona, Tucson 85724.

Abstract

We report the clinical and neuroimaging findings of a patient who sustained multiple cerebral infarcts after the ingestion of concentrated hydrogen peroxide solution sold as a "health food" product. An 84-year-old man sustained focal neurological deficits immediately after ingesting 30 mL of 35% hydrogen peroxide solution. Physical examination disclosed a left hemiparesis, frontal release signs, and cerebellar dysfunctions. Magnetic resonance imaging revealed multiple cerebral and cerebellar infarctions in the anterior, middle, and posterior vascular territories. The likely mechanism of pathogenesis involves cerebral oxygen gas embolization. The use of hyperbaric therapy should be considered in treating hydrogen peroxide poisoning.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Neurology (clinical)

Reference8 articles.

1. Dept of Health and Human Services. Hyper-Oxygenation Therapy. Rockville Md: US Food and Drug Administration Federal-States Relations; 1989.

2. Ingestion of 35% hydrogen peroxide;Humberston CL;Clin Toxicol.,1990

3. Death caused by hydrogen peroxide

4. Fatal poisoning with hydrogen peroxide

5. Beutler E. Red Cell Metabolism: A Manual of Biochemical Methods. 2nd ed. Orlando Fla: Grune & Stratton Inc; 1975:89-147.

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