1. From the Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute of Primary Care and Health Sciences, Keele University, United Kingdom (M.A.M.); Academic Department of Cardiology, Royal Stoke Hospital, Stoke-on-Trent, United Kingdom (M.A.M.); and Department of Cardiology, University Hospital Southampton, University of Southampton, United Kingdom (N.C.).