Chronic Extrinsic Cardiac Denervation by Regional Neural Ablation-Reference-Cited by-同舟云学术

Chronic Extrinsic Cardiac Denervation by Regional Neural Ablation

Published:1961-03 Issue:2 Volume:9 Page:275-281
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

COOPER THEODORE¹,GILBERT JOSEPH W.¹,BLOODWELL ROBERT D.¹,CROUT J. RICHARD¹

Affiliation:

1. Clinic of Surgery and Section of Experimental Therapeuties, National Heart Institute, Bethesda, Maryland

Abstract

A technique for complete extrinsic denervation of the heart by the ablation of neural structures in the mediastinum is described. The completeness of denervation was verified by direct electrical stimulation of the main vagal and sympathetic trunks. Total deple tion of myocardial catecholamines followed the procedure in chronic survivors. Animals prepared in this manner are useful in the study of the neurologically isolated heart and simulate this aspect of the problem of cardiac transplantation.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.9.2.275

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5. Sensitization of the denervated heart to adrenalin;BURRETT O. B.;Am. J. Physiol.,1940

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1. Quantitative immunohistochemical assessment of bovine myocardial innervation before and after cryosurgical cardiac denervation;Cardiovascular Research;1993-02-01

2. Cryosurgical denervation of the heart: Acute and chronic effects;The Journal of Thoracic and Cardiovascular Surgery;1990-08

3. Organization of the sympathetic postganglionic innervation of the rat heart;Journal of the Autonomic Nervous System;1989-12

4. Denervation supersensitivity of refractoriness in noninfarcted areas apical to transmural myocardial infarction.;Circulation;1987-08

5. Traumatic heart block and tachyarrhythmia induced by right ventricular impact;Journal of Electrocardiology;1985-01