Tolerance of Human and Rat Atrial Muscle to Hypothermia and Anoxia

Author:

NOREN GEORGE1,GOLDRING DAVID1,SLEATOR WILLIAM1

Affiliation:

1. the Departments of Pediatrics and Physiology, Washington University School of Medicine, Saint Louis, Missouri

Abstract

Evidence is presented which strongly suggests the preservation of contractility of human atrial muscle when hypothermia of 25 to 31 C. is used during anoxia. Parallel studies were carried out on albino rat atria which gave results similar to that of the human tissue. This report adds further evidence that hypothermia is valuable in open-heart surgery when anoxic is indicated for the repair of cardiac malformations.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference14 articles.

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4. Oxygen transport and utilization in dogs at low temperatures. Am. J;BIGELOW W. G.;Physiol.,1950

5. SWAN H. MARESH G. JOHNSON M. E. AND WARNER G.: Experimental creation and closure of interauricular septal Thoracic Surg. 20: 542 1950.

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