1. From the Departments of Surgery (N.D.A., J.B.W., P.K.S., J.E.S., G.C.H.) and Medicine (J.M.B.), and the Duke Clinical Research Institute (J.M.B., Y.Z., J.B.W.), Duke University Medical Center, Durham, NC; and Department of Surgery, University of Louisville, Louisville, KY (M.L.W.).