1. From Trinity Partners, Waltham, MA (M.Z., K.F., C.Y., H.A., Y.R., G.M., H.S.); Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT (K.S., D.W., S.S.); and Program in Health Services and Systems Research, Duke-NUS Graduate Medical School, Singapore, Republic of Singapore (D.M.).