Explainable Artificial Intelligence and Cardiac Imaging: Toward More Interpretable Models

Author:

Salih Ahmed1ORCID,Boscolo Galazzo Ilaria2,Gkontra Polyxeni3ORCID,Lee Aaron Mark1ORCID,Lekadir Karim3,Raisi-Estabragh Zahra14ORCID,Petersen Steffen E.1456ORCID

Affiliation:

1. William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, United Kingdom (A.S., A.M.L., Z.R.-E., S.E.P.).

2. Department of Computer Science, University of Verona, Italy (I.B.G.).

3. Department of de Matemàtiques i Informàtica, University of Barcelona, Spain (P.G., K.L.).

4. Barts Heart Centre, St Bartholomew’s Hospital, Barts Health NHS Trust, London, United Kingdom (Z.R.-E., S.E.P.).

5. Health Data Research UK, London (S.E.P.).

6. Alan Turing Institute, London, United Kingdom (S.E.P.).

Abstract

Artificial intelligence applications have shown success in different medical and health care domains, and cardiac imaging is no exception. However, some machine learning models, especially deep learning, are considered black box as they do not provide an explanation or rationale for model outcomes. Complexity and vagueness in these models necessitate a transition to explainable artificial intelligence (XAI) methods to ensure that model results are both transparent and understandable to end users. In cardiac imaging studies, there are a limited number of papers that use XAI methodologies. This article provides a comprehensive literature review of state-of-the-art works using XAI methods for cardiac imaging. Moreover, it provides simple and comprehensive guidelines on XAI. Finally, open issues and directions for XAI in cardiac imaging are discussed.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging

Reference78 articles.

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4. Artificial Intelligence in Cardiac Imaging

5. Mitchell, TM. Machine learning. Vol. 1. McGraw-hill New York; 1997.

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