1. From the Departments of Pharmacology (Y.N.A.N., M.L., R.E., T.M., C.C., J.C., E.J.M., P.J.J., M.-J.S.) and Pathology (C.L.-G.), Faculty of Medicine, and the Research Foundation (L.P., E.J.M.), University Clinic Hospital, University of Valencia, Spain; Glaxo Smith Kline (H.S.), Pa; the Research Foundation (J.C.), University General Hospital Consortium, Valencia, Spain; and Ciber CB06/06/0027 “Respiratory Diseases” Carlos III Health Institute (J.C., E.J.M., M.-J.S.), Spanish Ministry of Health, Spain.