1. From the Department of Cardiology (Y.F.), Renmin Hospotal, Wuhan University, Wuhan, China; the Department of Cell Biology (Y.F., F.S., J.L., and X.-C.J.), State University of New York Downstate Medical Center, Brooklyn, NY; Department of Medicine, Southern Medical University (F.S.), Guangzhou, China; Department of Biochemistry, School of Pharmacy (J.D.), Fudan University, Shanghai, China; and Lilly Research Laboratories (H.H.B., D.A.P., M.-S.K., and G.C.), Eli Lilly & Company, Indianapolis, Ind.