1. From Institute of Cellular and System Medicine (C.-H.C., M.-L.W., S.-F.Y.), National Health Research Institutes, Zhunan, Taiwan; College of Life Sciences (C.-H.C.), National Tsing Hua University, Hsinchu, Taiwan; Department of Neurology (Y.-C.L.), National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Biochemistry (M.D.L.), Boston University School of Medicine, Boston, Mass.