1. From the Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapparo, Japan (K.O., N.I., Y.O., S.T., A.N., S.H., Y.A., and H.T.); the Department of Molecular and Cellular Pathobiology and Therapeutics, Nagoya City University Graduate School of Pharmaceutical Sciences, Nagoya, Japan (S.F.); Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University, Sapparo, Japan (K.I. and K.O.).