1. From the Department of Pathology (S.M.S.) and Departments of Computer Science and Genome Sciences (S.-I.L.), University of Washington, Seattle, WA; Division of Biology, California Institute of Technology, Pasadena, CA (H.T.S.); Department of Biostatistics, University of California, Los Angeles, CA (S.H.); and Institute for Genomics and Multiscale Biology, Mt. Sinai School of Medicine, New York, NY (E.S.).