Low-Density Lipoprotein Receptor–Related Protein-1

Author:

Strickland Dudley K.1,Au Dianaly T.1,Cunfer Patricia1,Muratoglu Selen C.1

Affiliation:

1. From the Center for Vascular and Inflammatory Disease (D.K.S., D.T.A., P.C., S.C.M.), Departments of Surgery (D.K.S.), and Physiology (S.C.M.), University of Maryland School of Medicine, Baltimore.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Reference149 articles.

1. The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulin.

2. Purification of the rat hepatic α2-macroglobulin receptor as an approximately 440 kDa single chain polypeptide.;Moestrup SK;J Biol Chem,1989

3. Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.;Strickland DK;J Biol Chem,1990

4. Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the α2-macroglobulin receptor

5. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.

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